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Towards a TB vaccine: results of the phase IIb trial of M72/AS01[E] announced at the Union World Conference

 

 


Vice-Chancellor Prof. Mamokgethi Phakeng launches CIDRI-Africa's extended clinical research site

 

 


World TB Day 2019

Khutazwa Madolo appeared on Cape Town TV (DStv 263) in the run-up to World TB Day on 24th March, while Zandile Ciko & Andiswa Vazi were interviewed on Zibonele FM. CIDRI-Africa also participated in a World TB Day event at Thusong Multi-purpose Center in Khayelitsha on the 21st of March, along with partners CTV, Juicebox, Ihulmelo Lokhanyo Lwethu, City of Cape Town, and the Western Cape Department of Health.
View onto the Cape Town TV set
View of a TV showing Khutazwa Madolo and CTV interviewer
Andiswa Vazi in the Zibonele FM studio
Interior of the Thusong Multi-purpose Center on World TB Day 2019

UNAIDS Executive Director Michael Sidibé on World AIDS Day 2018

The theme of this year's World AIDS Day is "Live life positively: Know your HIV status". In this video, Michael Sidibé, UNAIDS Executive Director, explains the importance of testing:

Take the UNAIDS "Test Test" if you are unsure if you are at risk of HIV infection.


PredART trial results published in New England Journal of Medicine

An analysis published in the New England Journal of Medicine shows that a four-week course of moderate dose prednisone reduces the risk of TB-IRIS (tuberculosis-associated immune reconstitution inflammatory syndrome) by 30% in HIV-positive patients at high risk of developing the condition. This is the first trial to show that TB-IRIS can be prevented in these patients and represents an important contribution to the body of knowledge on management of HIV-TB co-infection. The findings have already resulted in changes to antiretroviral therapy guidelines around the world. 

In the PredART trial, researchers from CIDRI-Africa and the Institute of Tropical Medicine (Antwerp, Belgium) investigated whether providing people at high risk of TB-IRIS with moderate-dose prednisone could prevent development of the condition. The researchers enrolled HIV-positive patients who were initiating ART, who had started tuberculosis treatment within 30 days before enrolment, and who had a very low CD4 count

Watch a video on the trial below.


Union Scientific Director comments on M72 vaccine trial

Following the recent International Union against Tuberculosis and Lung Disease World Conference, Scientific Director Dr Paula Fujiwara commented on several new TB-related innovations, including the M72 vaccine trial in which CIDRI-Africa participated.


Visit by delegation from the People's Republic of China

Prof. Wilkinson and Dr Taeksun Song were pleased to welcome a delegation from the People's Republic of China led by Dr Guo Wanshen on the 10th of August 2018. The visitors reviewed clinical research and laboratory facilities associated with the Wellcome Centre for Infectious Diseases Research in Africa, and discussed ongoing collaborations and possible future ventures. The delegation included Dr Guo Wanshen (Director of Division of International Cooperation, Henan Provincial Commission of Health and Family Planning), Prof. Zhang Jiangong (President of Henan Cancer Hospital), and Dr Pan Ye (Vice President of Henan Provincial Chest Hospital).
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