With the fight against COVID-19 beset with concerns around the efficacy of vaccines in the face of a mutating virus, University of Cape Town virologists have shown that the body’s T cells maintain 85% of their capacity to detect variants, continuing to mount a substantial defence to prevent severe illness, hospitalisation and death.
Results published today in The Lancet Microbe detail analysis of 10 years’ health data, showing a relationship between HIV infection and acquisition of rifampicin resistance by tuberculosis. Rifampicin is an important first-line anti-tuberculosis medication.
Ongoing adaptive evolutionary convergence of the alpha, beta and gamma variants could lead to additional variants displaying any combination of increased transmissibility, altered virulence and/or increased capacity to escape population immunity.
A recent study from the University of Cape Town (UCT) confirmed that people living with diabetes (PLWD) are at an increased risk of severe COVID‑19 (hospitalisation and mortality). The findings were published in the journal Diabetes Research and Clinical Practice.
Increased IL-17A network connectivity serves as an indicator of elevated systemic inflammation and immune activation induced by advanced HIV infection, and predicts mortality in patients with HIV-tuberculosis co-infection.
No classes, tutorials, laboratory work or tests will take place on Monday, 19 April or Tuesday, 20 April. For safety reasons, campus will be locked down and no one, other than emergency services, will be allowed access.
South Africa’s vaccination drive began on Wednesday, 17 February 2021, at the Khayelitsha Hospital, with President Cyril Ramaphosa, Minister of Health Dr Zweli Mkhize and various frontline healthcare workers among the first to receive the Johnson & Johnson (J&J) vaccine.
Keertan is Head of the Division of Pulmonology in the Faculty of Health Sciences and leads the Centre for Lung Infection and Immunity, which is a UCT accredited centre with its clinical profiling facilities based at the University of Cape Town Lung Institute. He joins the Centre as a Contributing Investigator.